AlloDirect, Inc.

At AlloDirect, Inc., we believe the principles CMS is reinforcing – transparency, data integrity, and aligned agreements between OPOs, tissue banks, and care sites – are exactly what’s needed downstream in how tissue is priced, allocated, ordered, and used in surgery. We just submitted our first AATB abstract sharing six‑month pilot data from a direct digital procurement model connecting ASCs in real time to multiple AATB‑certified tissue banks. The platform aggregates 24,000+ SKUs into a single catalog with live inventory visibility and automates AATB‑compliant lot traceability, UDI capture, and recall‑readiness documentation at the point of order. Early results show this AI‑enabled biologics marketplace is on pace to save about $180,000 annually per ASC, cut order confirmation times from ~72 hours to under 15 minutes, and consolidate fragmented vendor relationships into a single digital channel while preserving surgeon preference coverage. As CMS tightens oversight of OPOs and donor hospitals through 2027, we’re working with tissue banks, OPOs, and ASCs to bring that same rigor to the "last mile" of tissue utilization – reducing expired grafts, strengthening traceability, and giving OPO‑ and AATB‑accredited partners real‑time visibility into how donated tissue reaches patients. "Turning Generosity Into Outcomes - Directly" Centers for Medicare & Medicaid Services Association for Advancing Tissue and Biologics Ambulatory Surgery Center Association (ASCA) Accreditation Association for Ambulatory Health Care (AAAHC) Joint Commission Free Market Medical Association U.S. DOGE Service OrthoCarolina OrthoVirginia OrthoAlliance Cleveland Clinic Orthopaedic Surgery & Sports Medicine Association of Organ Procurement Organizations (AOPO) Mayo Clinic Platform Atlas Healthcare Partners Tenet Healthcare HCA Healthcare Frist Cressey Ventures Abundant Venture Partners OCA Ventures MTF Biologics Plug and Play Health Mark Cuban Mark Cuban Cost Plus Drug Company, PBC Luke Cole

🚨 Healthcare supply chain attacks surged 55% in 2025. This week, Stryker became the latest victim. A cyberattack wiped Stryker’s global systems. CISA is investigating. Supply chains disrupted worldwide. The culprit? A massive, centralized enterprise environment with too many attack vectors, and too much sensitive data in one place. AlloDirect, Inc. was built lean on purpose. From day one, we made a deliberate design decision: we don’t touch PHI. We never store it. We don’t need it. Biologics procurement doesn’t require patient data, so we don’t ask for it. No API integrations pulling from your EHR. No bloated middleware sitting between you and your tissue bank. No rep-layer data exposure. Just direct connections, role-based authentication, and a minimal data footprint by design. In a world where supply chain attacks are the #1 healthcare cybersecurity threat in 2026, a smaller footprint isn’t a weakness - it’s a feature. Resilience by design. Procurement in seconds. No PHI needed. Ambulatory Surgery Center Association (ASCA) Surgery Ventures, powered by HCA Healthcare Illinois Bone & Joint Institute Illinois Bone & Spine Institute MTF Biologics OrthoCarolina OrthoVirginia OrthoAlliance UPMC OrthoIndy AMSURG Tenet Healthcare United Surgical Partners International, Inc Midwest Orthopaedics at Rush Ascension Ventures Fort Wayne Orthopaedics OCA Ventures Henry Ford Innovations Northwestern Innovation Institute Frist Cressey Ventures Sutter Health Sutter Health - Bay Area Free Market Medical Association 16 Tech Innovation District Journal of Orthopaedic Experience & Innovation Becker's Healthcare JIS Orthopedics Forté Sports Medicine and Orthopedics Indiana Orthopedic Institute ASC Data Arthrex Surgery Center Innovation Spine and Orthopedic Surgery Center Development - Meridian Surgical Partners Orthopedic ONE OrthoSouth - Orthopedic Care American Academy of Orthopaedic Surgeons (AAOS) American Alliance of Orthopaedic Executives (AAOE) Arizona Ambulatory Surgery Center Association Michigan Ambulatory Surgery Association The Journal of Bone and Joint Surgery, Inc. #AlloDirect #ASC #HealthcareCybersecurity #SupplyChain #Biologics #Startup https://lnkd.in/ePwGEusT

Proud to share that AlloDirect, Inc. has joined the Free Market Medical Association (FMMA). Their commitment to transparent, market-driven healthcare perfectly aligns with our mission to bring clear, predictable biologic procurement and direct connections to accredited tissue banks and ASCs. By standing alongside providers, employers, and solution partners who believe in up-front prices, value-based care, and willing-buyer/willing-seller relationships, we’re helping build a more sustainable and ethical supply chain for tissue distribution. Thank you to the FMMA community for welcoming us - excited to contribute to the movement toward transparency in healthcare purchasing. Ambulatory Surgery Center Association (ASCA) Illinois Bone & Joint Institute Illinois Ambulatory Surgery Center Association Keith Smith MTF Biologics AlloSource® Solvita DCI Donor Services, Inc. LifeLink Foundation Osiris Therapeutics OrthoCarolina OrthoVirginia OrthoAlliance Indiana Orthopedic Institute OrthoIndy AMSURG Tenet Healthcare Northwestern Medicine UPMC Supply Chain Management United Surgical Partners International, Inc SCA Health HCA HealthONE Sutter Health Surgery Ventures, powered by HCA Healthcare Orthopedic ONE OrthoSouth - Orthopedic Care Ascension Ventures Abundant Venture Partners Health Engine Fort Wayne Orthopaedics Midwest Orthopaedics at Rush JIS Orthopedics OCA Ventures Frist Cressey Ventures Henry Ford Innovations Healthcare Shares Oracle Health Samsung Healthcare

Becker's Healthcare ASC Review just highlighted “5 things to know about ASCs, supply chains,” and two themes stand out for every administrator and ASC leader: rising supply costs and the growing role of technology. What we’re hearing from ASC leaders matches the article: - Tariffs, recalls, and more complex procedures are putting sustained pressure on margins. - Case-level cost visibility and inventory tech are becoming essential to control spend. - Data-driven supply planning and vendor alignment are now central to financial sustainability. This is exactly why we built AlloDirect, Inc. We give ASCs real-time visibility into biologic and graft spend, automate case-level cost insights, and help standardize tissue and biologic choices without sacrificing surgeon preference; so supply chain becomes a lever for margin, not a source of uncertainty. AMSURG Ascension OrthoCincy OrthoAlliance OrthoCarolina OrthoIndy Surgery Ventures, powered by HCA Healthcare Surgery Center of Central Florida Ambulatory Surgery Center Association (ASCA) Orthopedic ONE United Surgical Partners International, Inc SCA Health Prisma Health Arizona Ambulatory Surgery Center Association Michigan Ambulatory Surgery Association Illinois Ambulatory Surgery Center Association Indiana University Health Optum Surgery Center of Fort Collins Surgery Center Of Oklahoma Palo Alto Surgery Center Sutter Health Health Engine Oracle Health If you’re rethinking your ASC supply chain strategy for 2026 and beyond, this Becker’s piece is worth a read: https://lnkd.in/g3upgn83 #MedTech #Supplychain #Healthcareinnovation

Thrilled to be joining Health Engine’s Cohort X alongside this impressive group of health innovators. 🚀 At AlloDirect, Inc. , we’re building an AI-powered biologics procurement platform that helps ASCs reduce costs, streamline ordering, maintain surgeon preferences, and stay compliant. This community will accelerate our journey to transforming healthcare at scale. Huge thank you to the Health Engine Team for the warm welcome and for the work you’re doing to support founders tackling real healthcare problems. We’re excited to learn from this cohort, share what we’re seeing in ASC supply chains, and collaborate on solutions that make care more affordable and efficient. University of California, Berkeley University of California, Berkeley, Haas School of Business HCA Healthcare SCA Health AMSURG Ascension Ascension Ventures Glenn Nanney, MD, MS Elevate Ventures Abundant Venture Partners OCA Ventures Andreessen Horowitz UPMC UPMC Supply Chain Management Northwestern Medicine Northwestern Innovation Institute SSV Michael Kelly VCU Health CommonSpirit Health Optum Kaiser Permanente Sutter Health LifeBridge Health Datavant Indiana University Health United Surgical Partners International, Inc Prisma Health OrthoCincy PELTO Health Partners OrthoCarolina Orthopedic ONE OrthoSouth - Orthopedic Care Surgery Ventures, powered by HCA Healthcare OrthoIndy Indiana Orthopedic Institute Ambulatory Surgery Center Association (ASCA) #HealthTech #MedTech #HealthcareInnovation #HealthEngine #ASCs #SupplyChain

Health Engine Cohort X is here! 🚀 Yesterday, we wrapped up orientation for our newest batch with 13 startups on the cutting-edge of Health-Tech innovation. So, what does Cohort X look like?: Gisens Biotech: A system of graphene biosensors enabling at-home kidney testing—an FDA breakthrough device—built by Luis Pierpauli and Esteban Piccinini Rovex Technologies Corporation: A healthcare robotics company developing autonomous mobile robots that tackle in-hospital patient transport, built by David Crabb CareLumi: A platform that automates healthcare credentialing and compliance so providers can bill faster, operate legally, and expand confidently, built by Shai B. G LNK (YC W25): AI platform with one of the largest HCP databases, unifying expert and clinical data to power faster, compliant research and partnerships, built by Rayan Ghandour AlloDirect, Inc.: An AI-powered marketplace that connects surgery centers and hospitals directly to tissue banks, eliminating the middleman in allograft procurement, built by Rhett Barker BedConnect: A SaaS platform that helps hospitals safely discharge patients faster by connecting them to post-acute care in real time-reducing delays and readmission, led by Lindsay A. Joseph Coreo, Inc.: An AI-powered oncology care coordination platform designed to close dangerous communication and execution gaps across the cancer care journey, led by Christie L. Clipper, DHA Yesod AI: AI teammates that automate clinical trial data analysis, compressing timelines from months to days, built by Bo Ci and Lizhong (Lucas) Liu Eyesight Electronics: Digital therapeutics and medical devices for at-home therapy and treatment of vision loss, built by Amin Rigi, Dr. Faiz Rigi, and Muhammad Ali Munir Medical Sphere An objective, third-party evaluation and benchmarking platform for healthcare AI on real medical cases to enable safe clinical adoption, built by Pedram Hosseini Anto Biosciences (YC F25): Biology AI lab building gut microbiome models to better understand drug failure and optimize specific drugs’ method of action, built by Arvid E. Gollwitzer and David de Gruijl Dr. Katz, Inc.: Healthcare knowledge platform built to help support mental health professionals in their practices, and support and educate patients through their treatment plans, built by Nathaniel Hundt MEGI Health: Focusing on building tools for preeclampsia diagnosis and long-term maternal care to support women’s heart health in pregnancy and beyond, built by Nina Sesto, PhD, and Ines Knezevic, MBA We're excited to have you join the Health Engine Network! #UCBerkeley #Healthcare #HealthTech #Startups #HealthEngine

Today, Premier Inc. launched a major, multi-year strategic initiative to help shape the future of healthcare. By partnering with Palantir Technologies, Microsoft and Databricks, we’re building an AI-powered, intelligent supply chain that gives healthcare leaders the real-time insight they need to navigate complexity, strengthen resilience and drive better performance — now and for the long term. This investment is about more than technology. It’s about enabling our members to make faster, smarter decisions, improve margins and outcomes, and lead with confidence in an increasingly uncertain environment. We believe the future of healthcare will be defined by intelligence, connectivity and execution at scale—and that future starts now. Read the full announcement: https://lnkd.in/gWbZRmGF

How many Becker's Healthcare articles do we need to read before anything actually changes? Week after week, it’s the same story across the country. “We’re working harder, but our margins keep getting thinner.” Labor, anesthesia, and supply costs keep climbing while reimbursement barely moves. The crisis continues and yet nearly every product vertical in this space is still running through the exact same legacy supply chain model. Redundant layers. Hidden spreads. Unnecessary middlemen. So why are we still following them? Why is a rep you haven’t seen in two years (if you even know who they are) making commission on your surgical products? Why is a 3rd party controlling what sits on your shelf or in your freezers? These questions are what led to AlloDirect, Inc. - the biologic GPO built for ASCs. Simply by routing biologic purchases through our software platform, facilities start saving overnight - no product switching, no formulary battles. Same product, 5% cost reduction guarantee, seamless democratized ordering and a compliance dashboard. It sounds too good to be true because the current system is that broken. Preserve surgeon preferences, consolidate your vendors, automate compliance and equip your operators to WIN. Peter Bravos, MD, MBA, FASA Charlene Cioe Summit Spine & Joint Centers OrthoCarolina OrthoCincy OrthoAlliance PELTO Health Partners OrthoIndy United Surgical Partners International, Inc SCA Health Vizient, Inc The Resource Group, Spend Management Solutions Ambulatory Surgery Center Association (ASCA) ASC Data Deena Edwards, RN, BSN, CCRN South Bend Orthopaedics Jeffrey Flynn Carmel Galster Sean Gipson Monte Kasten, MBA-Healthcare Entrepreneur Patrick Haley Neal Kaushal MD MBA Earl Kilbride MD MHA James Mitchell John Prunskis Marjorie Reiter AMSURG Forté Sports Medicine and Orthopedics Midwest Orthopaedics at Rush JIS Orthopedics Orthopedic ONE Fort Wayne Orthopaedics Tristate Orthopedics Center Premier Inc. US Orthopedic Alliance Vinod Dasa MD Value Health HealthTrust Performance Group https://lnkd.in/gJWbWawN

A new study published in Becker's Healthcare is putting consolidated ASC pricing dynamics back in the spotlight - finding that consolidation and vertical integration are reshaping how prices flow through the system. Regardless of ownership model, the implications are the same: ASC leaders need better visibility into what they're paying, what they're charging, and where the gaps are. Whether you're an independent ASC, part of a health system, or operating within a national platform - the ability to see, benchmark, and manage implant and biologic spend at a granular level has never been more critical. At AlloDirect, we partner with ASCs across the spectrum to deliver: ✅ Real-time visibility across vendors and facilities ✅ Benchmarking tools that support smarter negotiations with payers and suppliers ✅ A platform built to drive value for every stakeholder... Patients, Administrators, and Surgeons Consolidation isn't slowing down. The organizations that invest in pricing transparency and supply chain intelligence will be best positioned - no matter their ownership structure. Curious how AlloDirect can support your ASC strategy? Let's connect. AMSURG Ascension Ventures Ascension Abundant Venture Partners MTF Biologics OrthoCarolina Orthopedic ONE Cleveland Clinic Orthopaedic Surgery & Sports Medicine Orthopedic Center of Excellence at Denver Health SCA Health United Surgical Partners International, Inc Vizient, Inc Vizient Southeast Vizient Southern States, Inc. Indiana Orthopedic Institute OrthoIndy Tristate Orthopedics Center Indianapolis Business Journal Ambulatory Surgery Center Association (ASCA) Illinois Ambulatory Surgery Center Association Michigan Ambulatory Surgery Association Franciscan Alliance, Inc. HealthTrust Performance Group Lakeshore Bone & Joint Institute Full coverage from Becker's: https://lnkd.in/guThtdFj

The pressure is on for ASCs: higher-acuity cases, anesthesia costs up, labor shortages and implant costs consuming 40-50% of procedural spend. Vizient, Inc just released new guidance on how supply standardization is becoming the most sustainable path forward for ASC cost management: https://lnkd.in/g6wRaCFc The challenge? With over 6,000 Medicare-certified ASCs, 60% physician-owned, variation in implant technology, supplier mix, and purchasing habits is driving cost differences that don’t translate to better outcomes. At AlloDirect, this is exactly what we built our platform to solve: ✅ Real-time visibility into implant pricing across vendors and facilities ✅ Structured standardization that respects surgeon preference and clinical judgment ✅ Data that creates alignment between clinical and administrative teams As ASCs take on more complex orthopedic and spine procedures, the ability to manage implant spend at a granular level isn’t optional, it’s foundational to maintaining quality without eroding margins. Ready to see what evidence-based implant standardization looks like? Let���s connect. United Surgical Partners International, Inc HCA Healthcare SCA Health The Resource Group, Spend Management Solutions MTF Biologics OrthoCarolina OrthoAlliance Orthopedic ONE OrthoIndy Fort Wayne Orthopaedics Tri-State Orthopaedic Surgeons Tri State Surgical Healthcare Shares Ambulatory Surgery Center Association (ASCA) Ascension Ventures Ascension ASC Data Solvita Illinois Ambulatory Surgery Center Association Michigan Ambulatory Surgery Association AMSURG