Stanford University's Sustainable Vivarium Complex by Art's Way Scientific

In the 10 years since she joined Penn Medicine, University of Pennsylvania Health System, Donita Brady, whose lab studies what fuels cancer cells, has spearheaded efforts to make research recruitment more equitable. “Our goal is to inspire the next generation of potential world-changers and spark their passion for biomedical research,” she says. Read More: https://bit.ly/4n0XrLD

GREAT NEWS! 🧬 🔬 We have received funding from the University of Oslo to establish a Network for Spatial Multi-Omics together with Tuula Nyman, and Stig Ove Bøe. This initiative will strengthen collaboration between the Genomics (NorSeq-Cancer), Bioinformatics, and Flow Cytometry Core Facilities at the Institute for Cancer Research, together with the Proteomics Core Facility and the Core Facility for Advanced Light Microscopy. The network will boost expertise across our teams and enhance the services we provide to support pioneering research at Oslo University Hospital and University of Oslo. Idun Dale Rein, Susanne Lorenz, Eivind Hovig

🆕 Series: “𝐌𝐞𝐞𝐭 𝐭𝐡𝐞 𝐲𝐨𝐮𝐧𝐠 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐜𝐨𝐧𝐭𝐫𝐢𝐛𝐮𝐭𝐢𝐧𝐠 𝐭𝐨 𝐅𝐫𝐚𝐧𝐜𝐞 🇫🇷 - 🇨🇦 𝐂𝐚𝐧𝐚𝐝𝐚 𝐜𝐨𝐥𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐢𝐯𝐞 𝐩𝐫𝐨𝐣𝐞𝐜𝐭𝐬.” The High-Level Scientific Fellowship from the cooperation service of the French Embassy to Canada supports the mobility of young researchers (PhD candidates and postdoctoral fellows) from Canada to French research laboratories. The goal is to develop research partnerships and create new synergies. Every month, we publish the portrait of these young researchers, who explain how their experience in France has been an invaluable support to their research projects. EPISODE 1️⃣ – Mercury against cancer: the bold challenge of Yumeela Ganga-Sah, PhD, postdoctoral fellow at TRIUMF (Vancouver, B.C.) and 2025 laureate

🚨 New preprint alert! Excited to shared a new paper from my lab showing that #frontotemporal #dementia (FTD)-causing MAPT mutations (P301S, S305N, IVS10+16) hyperactivate rDNA transcription, leading to nucleolar enlargement, stress, and neurotoxicity, a previously underexplored pathological mechanism in tauopathies. This builds on our earlier work (Maina et al., 2018a,b) where we demonstrated that tau localises to the nucleolus and associates with the nucleolar remodelling complex, where it plays a role in regulating ribosomal DNA transcription and stress responses. Our current study, using SH-SY5Y cells and iPSC-derived neurons, is (to our knowledge) the first to directly link MAPT mutations to nucleolar dysfunction, suggesting dysregulated ribosome biogenesis may be an early contributor to neurodegeneration in FTD. 📖 Read the full preprint here: 🔗 https://lnkd.in/e-MJa2DT --- This specific work has been a long journey in the making. As an early-career researcher, pursuing unconventional questions, like tau’s role in the nucleus and nucleolus, hasn’t always been easy. Securing funding and support took time, but I am deeply grateful to the The Rainwater Charitable Foundation for believing in this direction. We are just getting started! Huge thanks to the entire team and our collaborators: Celeste Karch | Louise Serpell | Selina Wray | Thanks to Luc Buee for generously sharing some of the cellular models.

A new paper in Cambridge University Press's Journal of Clinical and Translational Science finds that travel distance to National Cancer Institute (NCI)-funded sites remains a key barrier for patients wanting to participate in #ClinicalTrials or research at these locations. “The evidence is clear that research opportunities for patients with cancer are not equally accessible to all, and multiple administrations have identified the same solution to this barrier,” says Sharon Shriver, Ph.D., Senior Analyst at ACS CAN and lead author. “Public policy and public funding can expand research opportunities into more rural areas where cancer incidence and mortality are higher than in urban areas. We hope that our study will help make the case with policymakers that now is the time for broadening the base of institutions receiving research infrastructure support.” Read more: https://lnkd.in/ePFB2WFg

A career in science is not easy. Funding can be hard to come by, breakthroughs can be few and far between and the road to publishing can be a long one. To be successful requires dedication for sure but sacrifice too? Is a career as a leading scientist compatible with raising a family, for example?   It is a question we put to the 2025 Brain Prize winners Michelle Monje and Frank Winkler. They received the Brain Prize for pioneering the field of Cancer Neuroscience and they both successfully manage to run a research lab, work in the clinic and raise a family.   In the first in the series of short Perspective films, in which we ask this year’s Brain Prize winners about science and life, Frank and Michelle share their perspectives on how their careers in science have been enriched by their families and their lives away from the lab. "You can do it all, but maybe not at the same time. There are years when you make a new human....and other years when you publish a Nature paper."

Researchers in the The Erik Jonsson School of Engineering and Computer Science at UT Dallas have developed biosensor technology that when combined with artificial intelligence shows promise for detecting lung cancer through breath analysis. Learn more: https://lnkd.in/gutusrPu

“The future is already here – it’s just not evenly distributed.” ― William Gibson The groundbreaking work of Dr. Shalini Prasad and her team at UT Dallas is a shining example of that truth — a glimpse into a future already unfolding, filled with world-changing possibilities. In an upcoming collaboration, we aim to partner with Dr. Prasad to advance a next-generation soil-sensing technology that continuously monitors soil health in one of our upcoming "Tiny Forest" deployments here in Dallas. Inspired by her pioneering biomedical sweat sensors which were first adapted for pilot testing at Restorative Farms’ Hatcher Station Training Farm in South Dallas, this innovation builds on the flexible electrochemical sensing systems Dr. Prasad originally designed for continuous monitoring of human biochemistry. These sensors have proven exceptionally sensitive, specific, and stable in complex physiological environments, capable of detecting biomarkers related to inflammation, infection, and hormonal changes. Now, Dr. Prasad’s team is translating those same principles to the soil ecosystem. The new soil sensors will provide real-time, continuous monitoring of several vital indicators of soil health: TOM, organic carbon,  moisture content and more. These metrics are central to understanding soil fertility, water retention, microbial vitality, and ultimately, the productivity and resilience of our growing soil food web systems.

📣 Owlstone Medical wins £36m award from Advanced Research Projects Agency for Health (ARPA-H) to develop at-home cancer detection tests  𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲 ⤵️ ⚙️ Medical 📈 Grant 💰 £36m 🤝 Advanced Research Projects Agency for Health (ARPA-H) 🧑 Billy Boyle; David Ruiz Alonso 🌎 Cambridge, United Kingdom 🔗 𝗶𝗻 𝗰𝗼𝗺𝗺𝗲𝗻𝘁𝘀

🎉 Please welcome and meet our new, first cohort of the T32 Oncological Data Science Program! Last but not least, we have Elena Nazarenko. Elena's project aims to develop new strategies for identifying effective therapies for rare cancers such as acral melanoma, where treatment options remain limited. Using a Bayesian variable selection framework, she will analyze high-dimensional multi-omics data to propose rational combination therapies and construct graphical models to infer cell–cell interactions within the tumor microenvironment. To maximize impact, she will also design interactive visualization tools to share our findings openly with researchers and clinicians.  ⭐ Elena's mentors are Ann Chen, PhD (Data Mentor) and Robert Judson-Torres, PhD (Cancer Biology Mentor). #GraduateProgram #Training #Education #CancerDataScience #TranslationalCancerResearch #T32ODSi