Graham Brooks

There's a new question in every health tech buying cycle that didn't exist 18 months ago: "Is this already on the roadmap of our foundation model vendor?" As we discussed in our 2026 healthcare predictions, we are entering a moment where the end user, clinicians and operators included, can increasingly build software themselves using agentic coding environments. In practice, this shows up when a CIO asks whether a proposed point solution is meaningfully different from what their existing foundation model could deliver with internal prompts, guardrails, and a few weeks of engineering time. This shift is quietly reshaping the competitive calculus. Startups selling into healthcare enterprises no longer compete only with the EHR vendor’s roadmap. They also compete with what a foundation model provider can plausibly ship for that customer, often faster and at lower marginal cost. Importantly, while the moat around building software is eroding, the moat around running software in healthcare is not. Healthcare enterprises are not set up to independently handle deep workflow integration, continuous iteration, reliability at scale, and governance across clinical, legal, and regulatory dimensions. That operational gap is where durable companies are still built. We expect this dynamic to introduce real friction into buying cycles for point solutions with thin moats. At the same time, it expands opportunity for companies with defensible data assets, deep workflow entrenchment, and true platform potential. Artera and Atropos Health are two strong examples from Breyer Capital's portfolio, both highlighted in the article. Special thanks to Brian Gormley for featuring our perspective in today's The Wall Street Journal piece on OpenAI and Anthropic's entry into healthcare. Jim Breyer Daniel Breyer Andre Esteva, PhD Brigham Hyde

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#AmTech Weekly Roundup: Ambience Healthcare raised $243 million in Series C funding from Oak HC/FT, Andreessen Horowitz, OpenAI, Kleiner Perkins, Optum Ventures, and Town Hall Ventures. Ambience is building AI documentation software to record patient appointments, generate comprehensive medical notes, and standardize coding/authorization workflows.   Michael Ng, Nikhil Buduma    Reveal Technology raised $30 million in Series B funding from Ballistic Ventures, Shield Capital, Booz Allen Hamilton, and others. Reveal’s two main offerings are 3D mappings generated from drone videos and mobile biometrics. They are deployed with the US Army, Special Operations Command, Marine Corps, and other NATO forces.   Garrett Smith    Prophet Security raised $30 million in Series A funding from Accel and Bain Capital Ventures. Prophet is applying agentic AI to Security Operations Centers (SOCs), or hubs for cybersecurity defenses within an organization.  Kamal Shah, Vibhav Sreekanti #VC #HealthTech #Healthcare #Defense #Cybersecurity

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Thanks to Erica Maissy for writing the latest series in our technology blog spotlights ~~ 🔬 Hormone Intelligence: A New Frontier for Personalized Health. Erica's writing explores the rapidly evolving world of hormone monitoring technology, a space that’s making major strides but also facing critical questions. From fertility tracking to stress management and beyond, innovators are pushing the boundaries of how we understand our bodies. 🚀 The shift from static, in-clinic hormone tests to continuous, at-home monitoring has opened doors to real-time insights — but it’s not without challenges. Accuracy, regulatory validation, and affordability remain key hurdles. For instance, while continuous glucose monitors (CGMs) transformed diabetes management, continuous hormone monitoring is far more complex due to slower hormone fluctuations and biological variability. 💡 We highlight a range of approaches — from micro-needle patches and sweat-based sensors to non-invasive temperature-based fertility tracking. Yet even the most promising solutions must prove their reliability against the gold standard of lab-based blood tests. As the global endocrine testing market is projected to reach $12.19B by 2030, we’re watching to see which technologies rise to the challenge. Link in the comments! #healthtech #hormones #personalizedmedicine

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A few weeks back, I watched Maggie Hott, GTM leader at OpenAI, confidently navigate her first board meeting at Unify. Having worked with her through Emergence Capital's Operator in Residence (OIR) program, seeing her immediately contribute valuable insights made me think about how most board members receive virtually no training for this critical role. At Emergence, we've built our firm around developing board excellence. We grow all our partners from within and have established a culture of mentorship focused on board service. Junior investors aren't thrown into the deep end—we pair them with senior GPs to observe effective board dynamics firsthand. My initial experience was at DroneDeploy alongside my partner Kevin Spain, where I got great mentorship before taking on independent board responsibilities. We extend this methodology to our OIR program, where operators learn how to be effective board members. Based on my experience mentoring directors, here are the fundamental principles I share with first-timers for how board members can best support founders: 1. Reframe the purpose: Problem-solving, not reporting If your board meeting is primarily reporting, you're wasting your management team's time. Information sharing should happen asynchronously, with board members engaging with materials before the meeting. This enables the live session to leverage collective intelligence on critical challenges. This rarely happens because many directors overextend themselves across too many boards—another reason we maintain a disciplined investment pace. 2. Master the Socratic approach The most valuable contribution often comes through thoughtful questions rather than declarative statements. Your objective is to enhance the decision-making capability of management. I enter each meeting with 1-3 specific areas where I know I can add value, focusing questions on these topics. 3. Follow-through separates professionals from amateurs Diligently document your commitments, establish clear action items, and execute them. It's crazy how just doing this proactively makes a board member stand out. 4. Understand your unique contribution to the board ecosystem A high-functioning board resembles a great basketball team—you need complementary skills, not redundant ones. In every meeting, I stay conscious of my distinct value relative to others in the room, whether that's SaaS expertise, AI knowledge, or a particular relationship dynamic with the CEO. I calibrate my role based on needs—sometimes assertively addressing areas where others have less experience, other times asking probing questions where fellow members have deeper expertise. -- To my knowledge, Emergence is the only VC firm with a formalized program dedicated to board excellence. It's an investment that yields returns where they matter most—in bending the odds of success for our founders. Founders, I'm curious: What board member behaviors have you found most valuable?

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Camber Creek led the $3.7 million Seed round for TwinKnowledge, which is tackling an important problem in the built environment. Construction projects get delayed and rework is required because of discrepancies across construction documents, submittals, requests for information, design, and other plans. TwinKnowledge’s AI Agents absorb structured and unstructured project data, surfacing and preventing conflicts before the work begins. We’re excited about our partnership with CEO Ivan Panushev and his team. #construction #AEC #AI #technology https://ow.ly/mBYX50VtaVG

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Great conversations at our WillowTree Ventures dinner with leaders across fintech and AI. A few themes stood out strongly: enterprises are leaning into AI for real efficiency gains, product and engineering orgs still set the agenda, and the whitespace in “boring” industries is wider than most people assume. It’s clear that the next breakout companies in AI for financial services won’t come from the obvious places. Thanks to everyone who joined - excited to keep working alongside founders building in these non-obvious, high-impact wedges.

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