Cincinnati Children's

Scientists at Cincinnati Children’s have developed a scalable new way to grow human gut organoids that are nearly 10x larger and mature twice as fast as previous methods. Using specially designed 3D-printed scaffolding trays, the research team created a “confined culture system” that enables intestinal, stomach and colon organoids to develop their own functional nervous systems — without needing nerve cells to be added artificially. This advance brings lab-grown human tissue closer to real-world therapeutic use, including disease modeling, drug testing and future regenerative medicine applications such as growing transplantable tissue for patients with intestinal damage or dysfunction. The study, published in Nature Biomedical Engineering, represents another major step forward in organoid medicine and tissue engineering. 🔗 Read more about the breakthrough on our Science Blog: https://lnkd.in/eivSUz5a 🔬 Research led by Holly Poling, PhD, and Maxime MAHE, PhD, with multiple Cincinnati Children's collaborators and experts from INSERM and Nantes Université. #Organoids #RegenerativeMedicine #StemCellResearch #BiomedicalEngineering

New research from Cincinnati Children's sheds light on the roots of chronic pain in neurofibromatosis type 1 (NF1). Scientists found that Schwann cells may trigger pain before tumors even appear by overproducing GDNF—pointing to opportunities for earlier, more targeted pain relief strategies. Published in Science Magazine, the study also shows that a MEK inhibitor reduced pain‑like responses in preclinical models, offering hope for improved quality of life for people living with NF1. Learn more on our Science Blog: https://lnkd.in/eQvmQ635 🔬 Research led by Namrata G.R. Raut, PhD, and Michael Jankowski, PhD #NF1 #PainResearch #Neuroscience #RareDisease #CincinnatiChildrens

We’re proud to share that Cincinnati Children’s has achieved HIMSS Stage 7 revalidation—an honor awarded to only a small number of healthcare organizations nationwide. This recognition underscores our continued commitment to leveraging digital capabilities to improve clinical outcomes, streamline workflows and enhance the care experience for patients and families. It reflects the collective efforts of teams across the organization working together to deliver: • Safer, more coordinated care • Real-time information sharing across providers • Data-driven insights to support decision-making Congratulations and thank you to all who contributed to this important milestone.

We're honored to receive this recognition, which reinforces our commitment to supporting recent graduates: https://lnkd.in/efQ23YaH. #WeAreCincyKids

Turning discovery into impact takes more than strong science. At a recent session at Cincinnati Children's with Chiesi Group, David Lough, PhD shared what industry looks for in early-stage innovation and academic partnerships. The takeaway: it is not just the idea. It is how well it is positioned for translation. Read more: https://lnkd.in/eMh9eTYX #Biotech #MedTech #TranslationalResearch #Innovation #LifeSciences #DigitalHealth #RareDisease

From improving infant outcomes to advancing compassionate NICU care, this year’s Perinatal Summit brought together nearly 150 healthcare professionals around a shared purpose: delivering the best care for families. We’re incredibly grateful to our regional and national speakers, who shared timely insights and helped shape care across the perinatal journey, and to everyone who made this event a success. #WeAreCincyKids #PerinatalCare

It’s Work With Us Wednesday! As National Nurses Month wraps up, we’re hiring for a variety of Nurse Practitioner roles. Ready to make an impact and join something special? Watch the video to learn more, explore our open roles, and apply today: https://lnkd.in/egJsxV39. You can also check out some of our "hot jobs" here: https://lnkd.in/g4vQ8p87. #WeAreCincyKids #NowHiring #NationalNursesMonth #NursesMonth 

Researchers have found that a new medication could cut relapse risk in half for kids who experience tics related to Tourette syndrome. Learn more about this chronic neurodevelopmental disorder, next steps, and additional details: https://lnkd.in/e2uyNasG. Cincinnati Children's Research Foundation

AI is changing how healthcare professionals work, and we have already embraced many of its revolutionary uses across our health system. We apply AI at both global and strategic levels to enhance our impact in key and relevant areas. And this week, during our first-ever AI Summit, our teams heard from our leaders about why and how we use this technology, and how we can apply it appropriately across our work. Our President & CEO, Steve Davis, MD MMM MS, also shared our “people-focused” vision and strategy for AI. Our approach amplifies our people’s impact by removing barriers, simplifying work, and giving teams more time to focus on what matters most. He also showed how AI is already helping us improve outcomes for kids, expand access and experience, and accelerate discovery and innovation. #WeAreCincyKids

Join us in congratulating Dr. Robert Shapiro, who recently received the Robert Denton Special Achievement Award. Each year, organizers present this statewide award recognizing the exceptional work that helps and empowers crime victims and survivors in Ohio. As he approaches retirement at the end of June, he spent decades advancing the protection and care of vulnerable children, pioneering child abuse pediatrics in Ohio and leading the development of our Mayerson Center for Safe and Healthy Children, the nation’s first hospital-based Child Advocacy Center. Watch as his colleagues share insight into his empathy and collaboration: https://lnkd.in/eDmU46vh, and learn more about the Mayerson Center: https://lnkd.in/e2wJ8Tf3. #WeAreCincyKids