This integrates a custom GUI event loop to be able to run polyscope asynchronously in a jupyter notebook.

pip install git+https://github.com/ugogon/interactive_polyscope.git

import polyscope as ps
import interactive_polyscope

%gui polyscope

ps.show()

#other commands

The important thing is the %gui polyscope magic command. It runs a custom event loop that handles the jupyter kernel REPL and the polyscope event loop.