Cell Discovery

Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases

Siyu Zhu
Ming-Qi Yan
Yi-Ping Li

Review Article 20 January 2026

Featured

Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD

Hu Feng
Jitan Zheng
Erwei Zuo
ArticleOpen Access13 May 2026
TGM2-mediated serotonylation of GPX4 confers ferroptosis resistance to promote gastric tumorigenesis

Junping Bai
Dandan Geng
Liwei An
ArticleOpen Access28 Apr 2026
ASO-based PKM splice-switching therapy increases anti-CTLA-4 antibody efficacy in pancreatic ductal adenocarcinoma

Lijie Han
Lina Gan
Adrian R. Krainer
ArticleOpen Access21 Apr 2026
Structural insights into the gating mechanism of the fission yeast phosphate exporter SpXpr1

Hui Yang
Yuechan Wang
Huaizong Shen
ArticleOpen Access15 Apr 2026

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Behind the Paper

In these Behind the Paper posts, our authors share the real stories behind the latest research papers, from conception to publication, the highs and the lows.

Browse articles

A spatiotemporal gating hypothesis for psilocybin plasticity: reconciling the 5-HT₂A-TrkB mechanistic paradox

Gang Pei
EditorialOpen Access29 May 2026
Selective cellular localization of UHRF1 safeguards mammalian zygotic genome activation and early embryonic development

Rui Yan
Xin Cheng
Fan Guo
ArticleOpen Access26 May 2026
WAT-to-BAT communication facilitates the sustained activation of BAT thermogenesis during cold exposure

Jieyuan Xue
Ding Chen
Xu-Yun Zhao
ArticleOpen Access26 May 2026
Exosomal ORF3a mediates lung-liver axis to dysregulate hepatic lipid metabolism in mild COVID-19

Yafei Qu
Jinglin Zhou
Qiming Liang
CorrespondenceOpen Access23 May 2026
Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment

Rui-chao Nie
Guo-sheng Hu
Wen Liu
ArticleOpen Access19 May 2026
A negative survival pressure selection system enables GPCR antagonist screening

Tao Xu
Qinxin Sun
Xiangyu Liu
CorrespondenceOpen Access13 May 2026
Receptor hyper-flexibility of human bitter receptor TAS2R4 revealed by cryo-EM structures in apo and tripeptide-bound states

Yuxia Qian
Ming Tan
Anna Qiao
CorrespondenceOpen Access13 May 2026
Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD

Hu Feng
Jitan Zheng
Erwei Zuo
ArticleOpen Access13 May 2026
ASB7 promotes osteosarcoma lung metastasis through ubiquitin-mediated degradation of ATF2

Yezi Zou
Jianliang Zhong
Liwen Zhou
ArticleOpen Access05 May 2026

Collections

Featured image of collection of Cell Discovery

Editor’s selections: top articles from the past 3 years

Cell Discovery is proud to present a collection of featured articles from the last 3 years that represent a broad scope in basic molecular and cell biology research.

Collection 21 Jun 2024

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