The 3Rs Collaborative (3RsC)

Our May More 3Rs features search hedges, aquatic course, webinars and more! 🐟

Don't miss Session 3 at the Spanish Language Lab Animal Symposium! Proud to see Lorena Garcia Menendez, DVM, MS, DACLAM presenting our collaborative systematic review on environmental health monitoring and advancing the conversation on modern rodent health monitoring strategies.

Executive Director of The 3Rs Collaborative, Megan LaFollette is heading to Washington, DC next week for the MPS World Summit, and we’re looking forward to connecting with the global community advancing microphysiological systems (MPS). If you’ll be attending, we hope you’ll engage with our network and join us at several sessions throughout the week 👇 👀 Where to find us 3Rs Collaborative member organizations will be active across the exhibit hall and scientific sessions throughout the conference. Keep an eye out for 3RsC pins and flyers—a great way to identify and connect with members of our initiative. 📅 Sessions and activities There will be 3 official opportunities to learn more about the 3RsC MPS initiative and our perspectives during the summit: 🔬 3RsC & FDA-CDER DILI Project Presentation Tuesday, May 26 | 3:25 - 3:45 PM | CC 204 Building confidence in MPS use in regulatory applications: The 3Rs Collaborative's & FDA-CDER's cross-platform DILI project, Nakissa Sadrieh 📊 Poster Presentation Thursday, May 28 | 4:00 - 5:30 PM | Poster #273 Advancing global adoption of microphysiological systems: Progress and impact of the 3Rs Collaborative's MPS initiative, Megan LaFollette This is your best opportunity to learn about the work the 3RsC is doing to advance MPS and chat about joining. 🌐 Roundtable Discussion Thursday, May 28 | 6:30 - 7:30 PM | CC 204 Stakeholders Response to the Workshop: Advancing Global Alignment on NAMs: Regulatory Roadmaps, Challenges, and Opportunities, Megan LaFollette This session will explore how the evolving international regulatory landscape is shaping the integration of NAMs, with a focus on key barriers and practical actions needed to enable globally aligned adoption.

We’re still reflecting on a fantastic 3Rs Sharing Conference earlier this month in Philadelphia at University of Pennsylvania, co-hosted with New Jersey Association for Biomedical Research and Pennsylvania Society for Biomedical Research (PSBR). It was a full day of thoughtful conversation and practical insights, bringing together colleagues from across academia and industry to share how the principles of Replacement, Reduction, and Refinement are shaping today’s research landscape. One message came through clearly: progress often comes from both big innovations and small, intentional changes—and collaboration is what moves it forward. Thank you to everyone who joined us and contributed to such an engaging event. And thank you to our presenting sponsor Charles River Laboratories and all our other sponsors & vendors! Tecniplast Allentown, LLC Sartorius Bio Serv Instech Laboratories, Inc. LICORbio Mouse Specifics, Inc. W.F. Fisher and Son Shepherd Specialty Papers, Inc. Unified Information Devices

⏰ Last chance to register Our webinar Ask the Experts: An Independent View on MPS is happening tomorrow. If you’re working with or exploring MPS as a replacement technology, this is a great opportunity to hear independent, cross-sector perspectives—and get your questions answered live. 👉 Register now: https://lnkd.in/g3X7ySMd #MicrophysiologicalSystems #MPS #3Rs #Replacement #NAMs

🔍 Upcoming Webinar | Ask the Experts: An Independent View on MPS Microphysiological systems (MPS) are gaining traction as a critical replacement technology within the 3Rs framework—but where does the field stand today, and what’s needed to advance broader, more effective use? Join us for an upcoming panel webinar, Ask the Experts: An Independent View on MPS Trends, Challenges, and Opportunities Ahead, featuring consultants from the 3RsC‑MPS Initiative. As independent experts working across technologies, sectors, and use cases, the panelists bring a unique, high‑level perspective on the MPS landscape. The discussion will address common questions from MPS end users and developers, key barriers to adoption, and opportunities to accelerate progress. 👉 Participants can submit questions during registration, and those submitted by May 12 will be given advanced consideration. Time will also be reserved for live audience questions during the webinar. Whether you’re developing MPS technologies, using them in practice, or exploring their role as replacement approaches, we invite you to join the conversation. 🔗 Register here: https://lnkd.in/g3X7ySMd 💬 Submit your questions by May 12 during registration Hossein Amirabadi Lowry Curley Norman Peterson Clive Roper BSc PhD CBiol CSci ERT FRSB #MicrophysiologicalSystems #MPS #3Rs #Replacement #NAMs #InVitroModels #ResearchInnovation

“Culture of care” can sound abstract, but when you look closely, many of its building blocks are already part of your institution. We’ve created a printable and editable poster illustrating the four pillars of a culture of care in animal research settings, designed to help teams make this concept visible, practical, and actionable. What makes this resource different? ✅ It’s customizable—you can add your own institution-specific contacts, programs, and resources ✅ It helps teams recognize what’s already working, not just what’s missing ✅ It supports conversations across roles, from animal care staff to researchers to leadership Culture of care isn’t a single program or policy. It’s a network of practices, people, and values that often already exist—just not always connected or named. This poster is meant to help bring those pieces together. Whether you’re building momentum or strengthening what’s already in place, we hpe this helps make culture of care feel tangible and shared. Available in two sizes to download: 👉 11 x 8.5 in. - https://lnkd.in/gri3iaw5 👉 24 x 18 in. - https://lnkd.in/gRsAZ2EY #CultureOfCare #AnimalResearch #ResearchCulture #LaboratoryAnimalScience #WellbeingAtWork

What if you could strengthen rodent health monitoring and replace animals at the same time? Environmental Health Monitoring (EHM) is helping institutions do exactly that—using environmental samples instead of extra animals to monitor colony health. ✅ No animals ✅ Better data ✅ Lower costs ✅ Stronger 3Rs alignment Through the 3Rs Collaborative Environmental Health Monitoring Initiative, partners across academia, industry, and government have come together to build practical, evidence‑based tools to support this transition: https://lnkd.in/gHbNUTYP Available resources include: • A publication page summarizing the evidence behind EHM • Real‑world implementation guidance • Case studies from institutions that have replaced sentinels • A mentorship program pairing you with experienced EHM leaders • And more! 📊 More than 35 institutions have already replaced sentinel animals with EHM—saving time and resources while improving animal welfare and data quality. Let’s modernize rodent health monitoring—together. #3Rs #AnimalWelfare #LaboratoryAnimalScience #EnvironmentalMonitoring #EHM #Replacement #ResearchInnovation

🔍 Upcoming Webinar | Ask the Experts: An Independent View on MPS Microphysiological systems (MPS) are gaining traction as a critical replacement technology within the 3Rs framework—but where does the field stand today, and what’s needed to advance broader, more effective use? Join us for an upcoming panel webinar, Ask the Experts: An Independent View on MPS Trends, Challenges, and Opportunities Ahead, featuring consultants from the 3RsC‑MPS Initiative. As independent experts working across technologies, sectors, and use cases, the panelists bring a unique, high‑level perspective on the MPS landscape. The discussion will address common questions from MPS end users and developers, key barriers to adoption, and opportunities to accelerate progress. 👉 Participants can submit questions during registration, and those submitted by May 12 will be given advanced consideration. Time will also be reserved for live audience questions during the webinar. Whether you’re developing MPS technologies, using them in practice, or exploring their role as replacement approaches, we invite you to join the conversation. 🔗 Register here: https://lnkd.in/g3X7ySMd 💬 Submit your questions by May 12 during registration Hossein Amirabadi Lowry Curley Norman Peterson Clive Roper BSc PhD CBiol CSci ERT FRSB #MicrophysiologicalSystems #MPS #3Rs #Replacement #NAMs #InVitroModels #ResearchInnovation

Our April More 3Rs features awards, surveys, webinars and more!