Singular Genomics

🚨🚨🚨 Last call for submissions for the G4X™ Spatial Research Challenge! Submit your proposal before May 22nd for one of two tracks for our In Situ Multiomic Service Research Grant: A large cohort study of up to 1000 samples or 3D spatial. Apply Now: https://lnkd.in/gFG8BCEW #SpatialBiology #TranslationalResearch #SpatialPathology #PrecisionMedicine

On 𝗝𝘂𝗻𝗲 𝟭𝟱𝘁𝗵, 𝗝𝗶𝘄𝗼𝗼𝗻 𝗣𝗮𝗿𝗸, 𝗣𝗵𝗗 𝗳𝗿𝗼𝗺 𝗪𝗲𝗶𝗹𝗹 𝗖𝗼𝗿𝗻𝗲𝗹𝗹 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲 will present on the latest data from SPOT-Met: a 1,000-patient spatial multi-omics atlas built on G4X to predict where colorectal cancer will spread before it does. • 𝗧𝗵𝗲 𝗦𝘁𝘂𝗱𝘆: 1,000 CRC primary tumors profiled with 1,000-plex RNA, protein, and fH&E at subcellular resolution in FFPE • 𝗧𝗵𝗲 𝗤𝘂𝗲𝘀𝘁𝗶𝗼𝗻: Can primary tumor spatial architecture predict organ-specific metastatic risk to liver, lung, or peritoneum? • 𝗧𝗵𝗲 𝗦𝗰𝗮𝗹𝗲: Paired with bulk RNA-seq, mutation/MSI status, and longitudinal follow-up across 500+ patients • 𝗧𝗵𝗲 𝗚𝗼𝗮𝗹: Shift metastatic risk stratification from retrospective staging to a prospective readout from the diagnostic biopsy Register here: https://lnkd.in/efWzMBeF #SpatialBiology #SpatialPathology #CancerResearch #Multiomics #G4X #ColorectalCancer

🚨One week left to submit a proposal for the 𝗚𝟰𝗫™ 𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗖𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲 If you know a translational team whose study design has been constrained by throughput, cost, or sample scale, pass this along. Proposals due May 22nd: https://lnkd.in/emxqdK4f #SpatialBiology #TranslationalResearch #Multiomics

Don't miss the opportunity to participate in the 𝗚𝟰𝗫™ 𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗖𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲! Here is what the flagship 1,000-sample award looks like in practice: • 𝟭,𝟬𝟬𝟬 𝗙𝗙𝗣𝗘 𝘀𝗮𝗺𝗽𝗹𝗲𝘀  profiled in a single, service-based study conducted by Singular • 𝗨𝗽 𝘁𝗼 𝟭,𝟬𝟬𝟬-𝗽𝗹𝗲𝘅 𝗥𝗡𝗔 + 𝟭𝟲-𝗽𝗹𝗲𝘅 𝗽𝗿𝗼𝘁𝗲𝗶𝗻 + 𝗳𝗛&𝗘  simultaneously, at subcellular resolution • 𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗲𝗱 𝗺𝘂𝗹𝘁𝗶𝗺𝗼𝗱𝗮𝗹 𝗿𝗲𝗮𝗱𝗼𝘂𝘁𝘀  at the single-cell level, from the same tissue section Proposals due May 22nd. Learn more and apply: https://lnkd.in/gZCRpf_2 #SpatialBiology #TranslationalResearch #Multiomics #PrecisionMedicine

Today, we are excited to announce John Stark as Chief Executive Officer of Singular! John brings more than 25 years of experience commercializing innovative technologies, scaling organizations, and building strategic partnerships across the life sciences industry. He joins us at an important moment as we build on the launch of G4X and enter our next phase focused on expanding adoption, deepening partnerships, and increasing the impact of multimodal spatial data across translational research, drug development, and future clinical applications. We are grateful to Joshua Stahl for his leadership as we sharpened focus on high-throughput spatial, strengthened operations, and launched G4X. We are pleased that Josh will continue to support the company as Independent Director on the Board. We are excited to welcome John and look forward to building on our momentum as we continue advancing spatial biology toward higher-impact applications in precision medicine. Read the announcement: https://lnkd.in/du7sGg5p #SpatialBiology #PrecisionMedicine #Biotech #Leadership #DrugDevelopment

That's a wrap on #AACR26! Five fun days here in San Diego, with 12 posters, 5 talks, and inspiring stories of how high-throughput spatial on G4X is impacting cancer research. #SpatialBiology #SpatialPathology #Multiomics #AACR2026 #CancerResearch

We’re proud to share a new publication in the Journal of Histotechnology: “TissuStamp: a novel high-throughput tissue transfer workflow for FFPE spatial biology assays.” The paper introduces a practical workflow for scaling FFPE spatial biology, enabling highly consistent transfer of up to 32 tissue regions on a single slide while preserving tissue morphology and multiomic assay performance. This method represents an important step toward more scalable spatial multiomics, leveraging the G4X for translational research and future clinical applications. Read the publication: https://lnkd.in/gyXWqa8v #SpatialBiology #FFPE #SpatialMultiomics #PrecisionMedicine #histology

#𝗔𝗔𝗖𝗥𝟮𝟬𝟮𝟲 continues! Stop by 𝗕𝗼𝗼𝘁𝗵 #𝟭𝟲𝟮𝟮 to see how G4X in situ multiomics and can power your next study, or learn more about our active research grant challenges! Swipe left to preview 12 posters featuring the G4X, then visit our AACR event page for full abstracts and schedules: https://lnkd.in/gbatS5AU

G4X is on display at #AACR2026! Stop by Booth 1622 to see the new era of high-throughput spatial, or apply for one of our two research grant challenges: - 1,000-Sample Spatial Study - 3D-Spatial Study #cancerresearch #AACR26 #spatialbiology

We are accepting proposals for the 𝟯𝗗 𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗦𝘁𝘂𝗱𝘆 award track, a grant dedicated to projects that require deep tissue reconstruction to map complex cellular relationships. The G4X platform’s repeatable performance enables robust serial section reconstruction, providing a higher-dimensional view of the tissue microenvironment. Every reconstruction includes integrated 1,000-plex RNA, 16-plex protein, and fH&E at subcellular resolution. 𝗣𝗿𝗼𝗽𝗼𝘀𝗮𝗹𝘀 𝗮𝗿𝗲 𝗱𝘂𝗲 𝗠𝗮𝘆 𝟮𝟮𝗻𝗱. Submit your 3D spatial project: https://lnkd.in/gEehdDXM #SpatialBiology #G4X #G4Xyz #3DBiology #TissueArchitecture #Pathology