PacBio

Special thank you to our Magenta Level sponsors for helping bring PRISM 2026 to life! Your support enables the genomics community to connect and explore the latest advancements in HiFi sequencing. Join leaders and innovators across genomics to examine new results and see how long-read sequencing is advancing complex analysis. You can also visit sponsor booths onsite to explore complementary solutions, gain practical insights, and discover new ways to enhance your workflows. Space is limited across our three global locations. Secure your spot: https://bit.ly/4slZxZs Thank you to our sponsors for their partnership: Agilent Technologies, Geneyx Genomex Ltd., Golden Helix, Inc., Opentrons Labworks Inc., QIAGEN, Sampled, SPT Labtech, Tecan #PacBioPRISM #PacBio #HiFisequencing #Genomics #Sponsors

Join PacBio at booth #3754 during the AACR Annual Meeting in San Diego. Discover how cancer researchers are advancing oncology with HiFi sequencing to reveal the full spectrum of cancer biology, including complex structural variants and epigenetic modifications, in a single workflow. Visit us to meet our experts and see live demonstrations of the Vega sequencing system. We are excited to discuss your sequencing projects and show how our innovations make tumor profiling more scalable and cost-effective than ever. Full program here: https://bit.ly/4uWzryz #PacBio #AACR26 #HiFisequencing #CancerResearch

Introducing: The HiFi Yield Leaderboard 🏁 We have highlighted high performers, and now we are making it a competition. Every three months we will be spotlighting the labs putting up the biggest HiFi numbers. Q1 is officially in. Princeton University Genomics Core Facility is leading the pack with 181 Gb of HiFi yield on Revio. Congrats to the team for setting an impressive pace of high-performing runs! Our next winner will be announced at the end of June and we cannot wait to see what kind of amazing work our community will produce. #PacBio #HiFisequencing #PrincetonUniversity #Q1Leaderboard

Long-read sequencing is reshaping how we study genomes, but what actually sets it apart? Think of it as the difference between reconstructing a 500-page novel from tiny, fragmented snippets versus using long runs of text that encompass entire paragraphs. Those longer "reads" provide the contextual information needed to place everything in the correct order, closing gaps and reducing errors that short-read methods often miss. If you’re looking for a clear, foundational overview (including how HiFi sequencing achieves 99.9% accuracy), this is a great place to start. 🔬 Explore the full breakdown: https://bit.ly/3PB0xLr #PacBio #HiFisequencing #LongReadSequencing #Genomics

Long-read sequencing is reshaping our understanding of human genetic variation, especially for structural variants that are difficult to resolve with short-read data. Join Dr. Michael Schatz from Johns Hopkins University for an ASHG Digital CoLab webinar as he highlights how PacBio HiFi whole genome sequencing is being applied across diverse populations. Drawing on insights from the All of Us initiative, he will unpack how long-read WGS uncovers previously hidden variants and evaluate their contribution to disease associations in GWAS and phenome-wide analyses. Register to learn how joint SNV and SV sets from long-read data are influencing discovery at scale and the growing importance of variant frequency resources in biobanks and clinical genomics. Sign up for the webinar: https://bit.ly/4bAW1oJ #PacBio #HiFisequencing #AllofUs #WGS #StructuralVariants #Bioinformatics

Join PacBio at ABRF 2026 to see how HiFi sequencing is advancing core facility and research workflows. Visit us at booth #801 to see the Vega system and speak with our technical experts about data generation and analysis. We are excited to discuss the new Revio SPRQ-Nx chemistry for $300 HiFi genomes at scale and the latest advances for the Vega system. Whether you are scaling whole genome sequencing or expanding your RNA and targeted offerings with Kinnex, we have the tools to help you get the most value from your HiFi data. Stop by to learn about our integrated multiomics, including 5mC and Fiber-seq for open chromatin. We look forward to connecting and discussing what matters most for your lab. #PacBio #ABRF2026 #HiFisequencing #ABRF

Sequencing in 2026: repeats → resolvable methylation → built in SVs → at scale AI → shaping discovery The work is more interesting than ever. These three interviews tap some of the sharpest minds in sequencing to tell us about the four-year problems solved in days, the edge cases people choose to chase, and results they never expected. Beyond the Bench season one is almost over. Stream the interviews while you still can: https://bit.ly/3KGNKVu #BeyondTheBench #PacBio #HiFisequencing

Successful AI models are built on data that is high-quality, complete, and rich in biological context. Basecamp Research is using PacBio HiFi sequencing to support its Trillion Gene Atlas initiative, an effort to dramatically expand access to evolutionary genetic diversity. By generating environmental and host-associated metagenomic data on the Revio system, they are building a richer map of biology that AI can learn from. Rather than learning on fragmented genetic snapshots, these foundation models are being trained on data that retains the broader structure of genomes. This high-resolution genomic analysis helps unlock insights that may otherwise remain hidden, accelerating the path from discovery to therapeutic application. Read the full story here: https://bit.ly/4svvj6N #PacBio #HiFiSequencing #Metagenomics #AI #BiologicalAI

Indexing, querying, and quantifying population-scale long-read RNA datasets. Amazing work by Xinchang Zheng, Fritz Sedlazeck, Ryan Layer and others. Congrats all, what a great collaboration! 🙏 preprint: https://lnkd.in/gEwJYTCh code: https://lnkd.in/gUrABc98

We gave early access of SPRQ-Nx chemistry to a select group of scientists. From improved performance to expanded application potential, beta testers like Katherine Munson from University of Washington are already seeing the workflow and economic benefits of what’s next for HiFi sequencing. Now it’s your turn to hear it firsthand. Join our on-demand webinar to dive into the full testimonial, real data, and what SPRQ-Nx chemistry could unlock for your research. Watch now: https://bit.ly/4szZAS9 #SPRQNx #PacBio #HiFisequencing #Genomics