Advanced Research Projects Agency for Health (ARPA-H)

Some ideas are too important to stay on the sidelines. ARPA-H is at #BIO2026 looking for the boldest thinking in health and biotechnology. We move with urgency to take ideas from concept to real world impact and deliver solutions patients are waiting for. Request a meeting and bring your best work forward. https://lnkd.in/esymXcKW 

In rural America, the nearest specialist can be hundreds of miles away. That’s a major reason that, right now, where you live determines how long you live.    We can do better. Through our PARADIGM program, researchers at the University of Michigan are developing VIGIL, AI guidance designed for mobile care delivery platforms that bring hospital level care directly to rural communities. That means advanced imaging, labs, and procedures delivered by a qualified medical provider, guided in real time by AI, in a parking lot near you. No 200-mile drive. No delayed diagnoses. Just first-class care, closer to home.    ARPA-H is reimagining healthcare so that where you live no longer determines the care you receive or the outcomes you face.    🔗 Read the full story: https://lnkd.in/ee9X5G7H Bon Ku Jason Corso 

"Healthy indoor air is the next great American public health investment." Last week, Rafid Fadul, Zivian co-founder and Chief Medical Officer of Advanced Research Projects Agency for Health (ARPA-H), participated in a Capitol Hill briefing with a group of public health, building science, defense, technology, and national security experts to make the case for buildings as a frontline defense for American biosecurity. Rafid outlined ARPA‑H’s BREATHE program, which aims to develop intelligent building systems capable of sensing threats, assessing health risks and triggering responses. Rafid has always been laser‑focused on systemic problems that impact human health. As ARPA‑H’s first CMO, he’s helping to accelerate breakthrough health technologies that can reshape how Americans live, heal, and access care. Rafid has always believed healthcare’s biggest challenges require infrastructure-level solutions. It’s exciting to see that vision driving impact at both ARPA-H and Zivian. 🚀 Read more: https://lnkd.in/eD9Xd8V4

Cleaner indoor air matters everywhere people gather. That is why ARPA-H’s BREATHE program is developing technologies that can monitor indoor air quality, detect potential health threats early, and help make indoor spaces healthier and safer. These innovations will be tested in places where cleaner air can have an enormous impact: 🍼Daycares, where more than 12 million American children under five spend their days. 🏫Schools, where asthma alone costs students more than 13 million school days every year.  🏥Hospitals, where cancer patients, transplant recipients, and people with COPD can face life-threatening risks from a single airborne exposure. 🪖Defense Health Agency medical centers, part of one of the largest healthcare networks in the country, serving 9.5 million beneficiaries. BREATHE performers Virginia Tech, Poppy, Mayo Clinic, and SafeTraces, Inc. are helping bring this work into real-world settings, from daycares and schools to hospitals and military medical centers. Protecting indoor air is one of the next frontiers in health. During Allergy and Asthma Awareness Month and beyond, ARPA-H is catalyzing innovation to make cleaner, safer air something people can count on wherever they learn, heal, and work. Learn more about BREATHE: https://lnkd.in/ej5XiVfe

ARPA-H invested $44M in 34 Lives and their No Kidney Left Behind project — using real-time organ rescue tech to recover kidneys once deemed unusable. From 400 → 500 → 600. The pace is accelerating. The science is working. Lives are being saved.

What matters in healthcare is what works. Data. Outcomes. Evidence that a treatment is delivering real, lasting results. For many veterans and Americans struggling with serious mental health conditions, emerging treatments like psychedelics have already been described as life changing. That was former Navy SEAL Marcus Capone’s experience after traveling abroad to receive ibogaine treatment when conventional options had failed him. He and his wife, Amber Capone, later co-founded VETS, Veterans Exploring Treatment Solutions, Inc to advocate for veterans seeking access to these therapies. But for treatments like these to become part of the American healthcare system, stories alone are not enough. We need rigorous, standardized ways to measure whether they work, who they work for, and how they can be delivered safely. That is what ARPA-H’s EVIDENT program is building. EVIDENT is developing FDA ready clinical endpoints and objective measurement tools to help evaluate behavioral health treatments with the same rigor expected across the rest of medicine. This Mental Health Awareness Month, ARPA-H is advancing a future where breakthrough mental health treatments are grounded in evidence, measured by outcomes, and available to the Americans who need them. https://lnkd.in/enmRA-ni

Americans with mobility limitations deserve assistive devices that do more than help them get from one place to another. What if mobility technology could help people navigate, interact with, and move through the world with greater safety, confidence, and independence?  ARPA-H’s Robotic Assistive Mobility and Manipulation Platform, or RAMMP, is working toward that future. Earlier this month, ARPA-H Program Manager Mansoor Khan joined colleagues from Meta’s AI for Good initiative at the AI+ Expo in Washington, D.C. to share footage from a recent University of Pittsburgh demonstration and discuss how open-source AI vision models are helping power RAMMP’s design. This work reflects what ARPA-H is built to do. Push beyond today’s limitations and create technologies that can dramatically improve people’s daily lives. Learn more about RAMMP and watch footage from the original demonstration in Pittsburgh: https://lnkd.in/ezKd4PaD Mansoor Khan AI at Meta Human Engineering Research Laboratories University of Pittsburgh Health Sciences University of Pittsburgh UPMC VA Health Systems Research Special Competitive Studies Project - SCSP      

What if our schools, hospitals, and workplaces could autonomously ensure the air we're breathing is healthy?  Through our BREATHE and PRO-MICROBE programs, ARPA-H teams are developing technologies that can help make indoor air cleaner and healthier, while also detecting dangerous pathogens before they spread. On Thursday, June 4, from 2–4 pm ET in Washington, DC, they will be presenting the technologies that will help shape the future of public health.  We invite stakeholders with an interest in healthy building design, environmental health, respiratory illness, and more, to connect with colleagues and explore what they are building. Note that space is limited and location will be provided upon registration. Please RSVP below. Jessica Green Yale University Mayo Clinic Poppy SafeTraces, Inc.Virginia Tech https://lnkd.in/ehTF2tNk 

We don't have an objective, biologically based test that can tell us if a patient has depression or anxiety. But we know these conditions are real, and we know they can have a profound impact on a person’s health and daily life. Veteran Chris Molaro, CEO and co-founder of ARPA-H performer NeuroFlow, built a digital platform to help better integrate mental health into the healthcare system and give providers clearer, more objective information to guide care. NeuroFlow’s platform helps identify behavioral health risks earlier at the population level and supports care teams in making smarter, more efficient decisions. The NeuroFlow team is also developing a population-scale framework to evaluate rapid-acting behavioral health interventions against real-world standards of care. This work is part of ARPA-H’s broader EVIDENT program, which aims to usher in a new era of behavioral health by developing and validating FDA-ready clinical endpoints that can help bring rapid-acting therapies to veterans and all Americans who need them. During Mental Health Awareness Month and beyond, ARPA-H is committed to building a future where mental health care is measured more rigorously, delivered more precisely, and treated with the urgency it deserves. NeuroFlow Christopher Molaro https://lnkd.in/eyJRBbNW