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Aug 16, 2015 at 20:39 comment added Cliff AB I would be very cautious using published literature on variable change over time to define large change. Your subpopulation will, necessarily, be different than the the other study's subpopulation and it may be reasonable that this difference affects rates of change: for example, if you are looking at a novel diet, you want not want to identify unusual change from estimates coming from a different study. Not saying that there are no measurements for which this approach could work, but it should be used with some caution.
Sep 1, 2014 at 18:36 comment added Joel W. Likely there is an existing, published literature on weight change over time. Your definition of a large (suspect) change could be based on that literature.
Sep 1, 2014 at 18:34 history undeleted Joel W.
Sep 1, 2014 at 18:33 history deleted Joel W. via Vote
Sep 1, 2014 at 18:06 comment added user603 the measures are taken over 10 years
Sep 1, 2014 at 13:52 history answered Joel W. CC BY-SA 3.0