A woman in a ball cap and black tank top holds a black and white image of the Moon printed on black acrylic. It can fold and is mounted on a black plastic mechanism with turning knobs affixed to the ends. There are out-of-focus shelves in the background with various items and books on them.

Moon Phase Flip Clock Is Fantastic

We love clocks, but we especially love unusual timepieces that aren’t just about showing the hour of the day. [Simone Giertz] built a flip clock moon phase tracker for a friend.

While in Egypt for Cairo Maker Faire, [Giertz] and [dina Amin] found some old flip clocks at a flea market and had to have them. [Amin] mentioned wanting to make a moon phase tracker with one, and [Giertz] decided to try her hand at making her own version. A side quest in more comfortable flying is included with the price of admission, but the real focus is the process of figuring out how to replicate the flip clocks original mechanism in a different size and shape.

[Giertz] cut out 30 semi-circle flaps from polystyrene and then affixed vinyl cut-outs to the flaps. The instructions for the assembly suggest that this might not be the best way to do it, and that printing stickers to affix to the flaps might work better since the cut vinyl turned out pretty fiddly. We really like the part where she built a grid jig to determine the optimal placement of the beams to keep the flaps in the right position after a disheartening amount of difficulties doing it in a more manual way. Her approach of letting it rest for twenty minutes before coming back to it is something you might find helpful in your own projects.

Best of all, if you want to build your own, the files are available for the flip moon station on the Yetch website. You’ll have to come up with your own method to drive it though as that isn’t in the files from what we saw.

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A Portable M4 Mac Mini

The Mac mini is the closest to an Apple-based SBC you can get, so it lends itself to unusual portable computers. [Scott Yu-Jan] is back to tackle a portable build using the latest and greatest M4 mini.

[Yu-Jan] walks us through his thought process of how to maximize the portability of the system without all that tedious mucking about with setting up a separate keyboard, monitor, and the mini while on the go. With the more complicated electronics, the monitor risked tipping the keyboard over when attached, particularly since [Yu-Jan] isn’t a fan of batteries for his portables.

By affixing the Mac mini to the side of the keyboard, it makes the whole thing easier to slip into a bag without being overly thick. We get a peek into his iterative process as well when he evaluates the build and decides that the closing of the lid wasn’t what he was hoping for. By adding some TPU rests for the monitor to rest on in the closed position, he says it’s really brought the whole project up a notch. We certainly have had our own projects where one little detail really moves it from sketchy to polished, and we appreciate when makers clue us in on where that happened for them.

You may recognize [Yu-Jan] from our previous coverage of his older portable all-in-one Mac mini and this luggable version where he explains why he doesn’t like laptops. If you like your computers more stationary, how about some G4 iMacs with the newer internals from an M-series mini?

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A black and white slide with the Supercon 8 logo in the top left, the text, "Nanik Adnani" and "A Hacker's Guide to Analog Design in a Digital World" is in the bottom left. To the right is a circularly cropped image of An image of a college student in glasses and a cap sitting with a black camera in his lap.

Supercon 2024: A Hacker’s Guide To Analog Design In A Digital World

We often think of analog computing as a relic of the past, room-sized monstrosities filled with vacuum tubes doing their best to calculate Monte Carlo simulations or orbital velocities. Analog isn’t as dead as it might seem though, and analog mix signal design engineer [Nanik Adnani] gave us a crash course on analog circuits at Supercon 2024.

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A picture of a single water droplet on top of what appears to be a page from a chemistry text. An orange particle is attached to the right side of the droplet and blue and black tendrils diffuse through the drop from it. Under the water drop, the caption tells us the reaction we're seeing is "K2Cr2O7+ 3H2O2 + 4H2SO4 = K2SO4+Cr2(SO4)3+7H2O+3O2(gas)"

Water Drops Serve As Canvas For Microchemistry Art

If you’re like us and you’ve been wondering where those viral videos of single water drop chemical reactions are coming from, we may have an answer. [yu3375349136], a scientist from Guangdong, has been producing some high quality microchemistry videos that are worth a watch.

While some polyglots out there won’t be phased, we appreciate the captioning for Western audiences using the elemental symbols we all know and love in addition to the Simplified Chinese. Reactions featured are typically colorful, but simple with a limited number of reagents. Being able to watch diffusion of the chemicals through the water drop and the results in the center when more than one chemical is used are mesmerizing.

We do wish there was a bit more substance to the presentation, and we’re aware not all readers will be thrilled to point their devices to Douyin (known outside of China as TikTok) to view them, but we have to admit some of the reactions are beautiful.

If you’re interested in other science-meets-art projects, how about thermal camera landscapes of Iceland, and given the comments on some of these videos, how do you tell if it’s AI or real anyway?

A human hand in a latex glove holds a test tube filled with red liquid labeled H5N1. In the background is an out of focus image of a chicken.

Preparing For The Next Pandemic

While the COVID-19 pandemic wasn’t an experience anyone wants to repeat, infections disease experts like [Dr. Pardis Sabeti] are looking at what we can do to prepare for the next one.

While the next pandemic could potentially be anything, there are a few high profile candidates, and bird flu (H5N1) is at the top of the list. With birds all over the world carrying the infection and the prevalence in poultry and now dairy agriculture operations, the possibility for cross-species infection is higher than for most other diseases out there, particularly anything with an up to 60% fatality rate. Only one of the 70 people in the US who have contracted H5N1 recently have died, and exposures have been mostly in dairy and poultry workers. Scientists have yet to determine why cases in the US have been less severe.

To prevent an H5N1 pandemic before it reaches the level of COVID and ensure its reach is limited like earlier bird and swine flu variants, contact tracing of humans and cattle as well as offering existing H5N1 vaccines to vulnerable populations like those poultry and dairy workers would be a good first line of defense. So far, it doesn’t seem transmissible human-to-human, but more and more cases increase the likelihood it could gain this mutation. Keeping current cases from increasing, improving our science outreach, and continuing to fund scientists working on this disease are our best bets to keep it from taking off like a meme stock.

Whatever the next pandemic turns out to be, smartwatches could help flatten the curve and surely hackers will rise to the occasion to fill in the gaps where traditional infrastructure fails again.

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An illustration of two translucent blue hands knitting a DNA double helix of yellow, green, and red base pairs from three colors of yarn. Text in white to the left of the hands reads: "Evo 2 doesn't just copy existing DNA -- it creates truly new sequences not found in nature that scientists can test for useful properties."

LLMs Coming For A DNA Sequence Near You

While tools like CRISPR have blown the field of genome hacking wide open, being able to predict what will happen when you tinker with the code underlying the living things on our planet is still tricky. Researchers at Stanford hope their new Evo 2 DNA generative AI tool can help.

Trained on a dataset of over 100,000 organisms from bacteria to humans, the system can quickly determine what mutations contribute to certain diseases and what mutations are mostly harmless. An “area we are hopeful about is using Evo 2 for designing new genetic sequences with specific functions of interest.”

To that end, the system can also generate gene sequences from a starting prompt like any other LLM as well as cross-reference the results to see if the sequence already occurs in nature to aid in predicting what the sequence might do in real life. These synthetic sequences can then be made using CRISPR or similar techniques in the lab for testing. While the prospect of building our own Moya is exciting, we do wonder what possible negative consequences could come from this technology, despite the hand-wavy mention of not training the model on viruses to “to prevent Evo 2 from being used to create new or more dangerous diseases.”

We’ve got you covered if you need to get your own biohacking space setup for DNA gels or if you want to find out more about powering living computers using electricity. If you’re more curious about other interesting uses for machine learning, how about a dolphin translator or discovering better battery materials?

A black and blue swirl background with the logo of a blue dolphin over the word DolphinGemma with dolphin in white and Gemma in blue

DolphinGemma Seeks To Speak To Dolphins

Most people have wished for the ability to talk to other animals at some point, until they realized their cat would mostly insult them and ask for better service, but researchers are getting closer to a dolphin translator.

DolphinGemma is an upcoming LLM based on the recordings from the Wild Dolphin Project. Using the hours and hours of dolphin sounds recorded by researchers over the decades, the hope is that the LLM will allow us to communicate more effectively with the second most intelligent species on the planet.

The LLM is designed to run in the field on Google Pixel phones, due to it being based on Google’s in-house Gemini product, which is a bit less cumbersome than hauling a mainframe on a dive. The Wild Dolphin Project currently uses the Georgia Tech developed CHAT (Cetacean Hearing Augmentation Telemetry) device which has a Pixel 6 at its heart, but the newer system will be bumped up to a Pixel 9 to take advantage of all those shiny new AI processing advances. Hopefully, we’ll have a better chance of catching when they say, “So long and thanks for all the fish.”

If you’re curious about other mysterious languages being deciphered by LLMs, we have you covered.

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